Ginger root (Zingiber officinale) has been used for thousands of years to treat stomach ailments and nausea. Due to this you will find a great number of powdered ginger supplements on the market. The active constituents of ginger include gingerols and gingerdiols. However, these compounds make up less than five percent of the dried root (1).
A serotonin receptor in the brain known is responsible for most feelings of nausea and vomiting. Prescription antiemetic drugs antagonize the activity of this receptor. Popular medications involved in this activity include Ondansetron or Zofran and Metoclopramide and are often used for morning sickness during pregnancy. Moreover, gingerols have shown the same effectiveness as these prescription medications by completely inhibiting induced vomiting (2). Only recently has the functional mechanism of gingerols been elucidated and in fact, gingerols function by antagonizing the same receptor associated with nausea as do these prescription medications (3).
As only a small fraction of dried ginger root contains the active constituents, dosaging and the relative effectiveness has been an issue in the past with taking the powdered herb (1). Here at Elk Haven Herbals only pure gingerols and gingerdiols are used in the making of our Herbal Anti-Vertigo/Emetic. Contains 30 doses.
1. Yanke Yu, Suzanna Zick, Xiaoqin Li, Peng Zou, Benjamin Wright, and Duxin Sun (2011). “Examination of the pharmacokinetics of active ingredients of ginger in humans”. The AAPS Journal, Vol. 13, No. 3: 417-426.
2. Johji Yamahara, Huang Qi Rong, Yoshikazu Naitoh, Tetsuya Kitani, and Hajime Fujimura (1989). ”Inhibition of cytotoxic drug-induced vomiting in suncus by a ginger constituent”. Journal of Ethnopharmacology, 27.
3. Abdel-Aziz H, A. Nahrstedt, F. Petereit, T. Windeck, M. Ploch, and E.J. Verspohl (2005). “5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome Zingiber officinale” Planta Med, 71: 609-616.
*Results may vary. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement